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Drug2Transporters
Transporters2Drug
Drug-Drug Interaction
SMILES or Name
Example
Inhibitor/substrate:
-
Inhibitor
Substrate
In Vivo/In Vitro:
-
In Vitro
In Vivo
Gene Name:
-
Slc22a12
Slco1a2
SLC6A1
SLC6A6
SLC40A1
SLC6A3
SLC29A2
SLC7A1
SLC1A7
SLC19A2
Slc22a6
Abcg2
SLC12A4
Slc1a2
SLC51B
Slc47a1
SLC28A2
SLCO6A1
Slco1a4
SLC38A1
Slc22a1
SLC18A3
SLC43A3
SLC6A11
SLC20A2
SLCO2B1
SLCO1A2
AQP7
Slco2a1
SLC1A3
Slc22a11
SLC36A2
SLC7A5
Slc47a2
SLC12A2
SLC6A2
ABCB11
ABCC6
SLC5A2
SLC25A20
SLC15A2
SLC7A10
SLC26A6
SLC12A1
SLC38A4
Slco1a3
SLC52A2
SLC3A1
SLC1A5
SLC19A1
SLC2A5
SLC19A3
SLC5A1
SLC38A3
Slco1a6
SLC34A2
SLC6A14
SLC12A5
SLC7A11
SLC17A1
SLC43A1
SLC22A11
SLC25A10
SLC22A12
SLC26A9
SLC44A1
Slc29a1
ABCC4
SLCO3A1
SLC51A
Slc10a2
SLC47A1
SLC38A2
ABCC9
SLC65A2
SLC5A6
Abcc1
SLC22A3
SLC4A5
SLC22A7
Slc22a2
Slc28a2
SLC1A2
SLCO4C1
ABCG1
SLC4A3
Slc15a2
SLC44A2
SLC46A1
Slc29a2
Abcc6
abcb4
SLC10A2
Slc29a4
SLC2A2
SLC2A9
ABCC8
Slc7a5
SLCO1B1
Slc6a6
SLC2A4
SLC38A5
SLC42A3
SLC16A7
SLC18A2
SLCO5A1
ABCC11
SLC34A1
Slc15a1
Slc22a7
Slco4c1
SLCO2A1
Slco1b2
Slc22a8
SLC47A2
ABCC7
SLC28A1
SLC5A4
Slc16a6
SLC22A6
SLC6A4
SLC6A5
SLCO1C1
ATP12A
SLC16A1
Slc28a3
Slco2b1
Slc18a2
MTTP
SLC25A24
Slc16a1
SLC2A1
SLC10A1
Slco1a1
ABCC3
SLC12A3
SLC1A1
RALBP1
SLC6A19
Slc22a3
Slc34a1
SLC1A6
Slc22a5
Slc10a1
SLC22A2
Slc22a4
SLC6A13
SLC37A4
ABCB1
ABCC10
SLCO1B3
SLC36A1
SLC22A4
Abcc5
SLC23A1
Slc28a1
ABCG2
SLC4A9
SLC5A7
SLC4A2
Abcc4
ABCC5
Abcb1
SLC18A1
SLC52A3
SLC51A or SLC51B
SLC27A1
SLC5A3
Abcc3
SLC22A8
SLCO4A1
ATP7B
Abcb11
SLC16A6
Abcc2
SLC2A3
SLC4A4
SLC29A1
SLC22A5
SLC1A4
SLC26A7
Slco1a5
SLC31A1
SLC6A12
SLC28A3
ABCC2
ABCC1
SLC6A7
SLC16A4
SLC22A1
SLC29A4
SLC15A1
SLC5A5
SLC32A1
SLC6A9
Slc5a1
ABCA1
Species:
-
Animal (unspecified)
Baboon
Cow
Dog
Fish
Frog
Guinea pig
Hamster
Human
Killifish
Mammal (unspecified)
Monkey
Mouse
Mussel
Pig
Plasmodium falciparum
Rabbit
Rat
Rodent (unspecified)
Sheep
Streptomyces peucetius
Research Methods:
-
Animal
Cell line
In Vivo
Lactococcus lactis
ND
Oocyte
Primary cells
Proteoliposome
Recombinant
Tissue
Vesicle
Yeast
Transport Parameters:
-
% Inhibition
% maximum response
% transported
1/RI50
Alpha max
Amount
AUC
Biliary
Bioavailability
Brain/plasma ratio
C/M
Cavg
Cellular accumulation
CL
Cmax
Cmin
Concentration
Dose-dependent effect
Drug Transport
EC200
EC50
ED50
Efflux ratio
Emax
f2
FC
Fetal/maternal
Fg
Fh
FICI
Flow
Fluorescence intensity
flux rate(J)
ft
GI50
GI50
Hill coefficient
I0.5
IC20
IC25
IC50
IC90
Imax
Inhibition Activity
inhibitor or not
ka
Kact
Kd
Kel
Ki
Km
Kp
milk/plasma
mRNA
MRT
net flux ratio
Not Determined
Papp
Pc
Pdif
Peff
Permeability
PK (unspecified)
Protein expression
PSeff
PSinf
Resistance
Substrate Activity
Substrate or not
T1/2
Tmax
Transport Change
Transport Rate
Transport ratio
unspecified
Drug uptake
Urine excretion
Vd
Vmax
Vz
Submit
Tip
Before submitting
, users should prepare a valid SMILES in case of errors.
Transporter Name
-
OCT1
OCT2
OCT3
ABCA1
ABCC
ABCG1
AQP7
ASBT
ASCT2
B0AT1
BCRP
BSEP
CNT1
CNT2
CNT3
CTR1
DrrAB
EAAT2
ENBT1
ENT(unspecified)
ENT1
ENT2
ENT4
GLUT9
Hepatic uptake transporters(unspecified)
LAT
LAT1
MATE(unspecified)
MATE1
MATE2
MCT
MCT1
MCT4
MCT6
MDR1
MRP
MRP1
MRP10
MRP2
MRP3
MRP4
MRP5
MRP6
MRP7
MRP8
MTP
NaPi-IIa
Non-ABCG2 Unspecified
Non-OCT2 Unspecified
NPT1
NTCP
Nucleoside transporters (unspecified)
OAT
OAT1
OAT1P3
OAT2
OAT3
OAT4
OATP
OATP1
OATP1A
OATP1A1
OATP1A2
OATP1A3
OATP1A4
OATP1A5
OATP1A6
OATP1B
OATP1B1
OATP1B2
OATP1B3
OATP1C1
OATP1D1
OATP2
OATP2A1
OATP2B1
OATP2P1
OATP3
OATP3A1
OATP4A1
OATP4C1
OATP5A1
OATP6A1
OCT(unspecified)
OCTN(unspecified)
OCTN1
OCTN2
OST alpha/beta
PCFT
PEPT
PEPT1
PEPT2
PfCRT Dd2
PMAT
Proton pump
Proton-coupled organic cation antiporter
Reduced folate carrier
SGLT1
SGLT2
SLC(unspecified)
SMVT
TAUT
Transporter(unspecified)
URAT1
VMAT2
AE2
AE3
AE4
ASC1
ASCT1
ATB0+
ATP7B
BGT1
CACT
CAT1
CHT
CTL1
CTL2
DAT1
DIC
EAAT1
EAAT3
EAAT4
EAAT5
FATP1
FLOT1
G6PT
GABT1
GAT2
GAT3
GLUT1
GLUT2
GLUT3
GLUT4
GLUT5
GLYT1
GLYT2
IREG1
KCC1
KCC2
LAT3
MCT2
NBAT
NBCe1
NBCe2
NCC
NET
NIS
NKCC1
NKCC2
NPC1L1
NPT2A
NPT2B
OSTalpha
OSTbeta
PAT1
PAT2
PIT2
PROT
RALBP1
RFVT2
RFVT3
RHGK
SCAMC1
SERT
SGLT3
SLC26A6
SLC26A7
SLC26A9
SLC7A11
SMIT
SNAT1
SNAT2
SNAT3
SNAT4
SNAT5
SUR1
SUR2
SVCT1
THTR1
THTR2
VACHT
VIAAT
VMAT1
Gene Name:
-
Slc22a12
Slco1a2
SLC6A1
SLC6A6
SLC40A1
SLC6A3
SLC29A2
SLC7A1
SLC1A7
SLC19A2
Slc22a6
Abcg2
SLC12A4
Slc1a2
SLC51B
Slc47a1
SLC28A2
SLCO6A1
Slco1a4
SLC38A1
Slc22a1
SLC18A3
SLC43A3
SLC6A11
SLC20A2
SLCO2B1
SLCO1A2
AQP7
Slco2a1
SLC1A3
Slc22a11
SLC36A2
SLC7A5
Slc47a2
SLC12A2
SLC6A2
ABCB11
ABCC6
SLC5A2
SLC25A20
SLC15A2
SLC7A10
SLC26A6
SLC12A1
SLC38A4
Slco1a3
SLC52A2
SLC3A1
SLC1A5
SLC19A1
SLC2A5
SLC19A3
SLC5A1
SLC38A3
Slco1a6
SLC34A2
SLC6A14
SLC12A5
SLC7A11
SLC17A1
SLC43A1
SLC22A11
SLC25A10
SLC22A12
SLC26A9
SLC44A1
Slc29a1
ABCC4
SLCO3A1
SLC51A
Slc10a2
SLC47A1
SLC38A2
ABCC9
SLC65A2
SLC5A6
Abcc1
SLC22A3
SLC4A5
SLC22A7
Slc22a2
Slc28a2
SLC1A2
SLCO4C1
ABCG1
SLC4A3
Slc15a2
SLC44A2
SLC46A1
Slc29a2
Abcc6
abcb4
SLC10A2
Slc29a4
SLC2A2
SLC2A9
ABCC8
Slc7a5
SLCO1B1
Slc6a6
SLC2A4
SLC38A5
SLC42A3
SLC16A7
SLC18A2
SLCO5A1
ABCC11
SLC34A1
Slc15a1
Slc22a7
Slco4c1
SLCO2A1
Slco1b2
Slc22a8
SLC47A2
ABCC7
SLC28A1
SLC5A4
Slc16a6
SLC22A6
SLC6A4
SLC6A5
SLCO1C1
ATP12A
SLC16A1
Slc28a3
Slco2b1
Slc18a2
MTTP
SLC25A24
Slc16a1
SLC2A1
SLC10A1
Slco1a1
ABCC3
SLC12A3
SLC1A1
RALBP1
SLC6A19
Slc22a3
Slc34a1
SLC1A6
Slc22a5
Slc10a1
SLC22A2
Slc22a4
SLC6A13
SLC37A4
ABCB1
ABCC10
SLCO1B3
SLC36A1
SLC22A4
Abcc5
SLC23A1
Slc28a1
ABCG2
SLC4A9
SLC5A7
SLC4A2
Abcc4
ABCC5
Abcb1
SLC18A1
SLC52A3
SLC51A or SLC51B
SLC27A1
SLC5A3
Abcc3
SLC22A8
SLCO4A1
ATP7B
Abcb11
SLC16A6
Abcc2
SLC2A3
SLC4A4
SLC29A1
SLC22A5
SLC1A4
SLC26A7
Slco1a5
SLC31A1
SLC6A12
SLC28A3
ABCC2
ABCC1
SLC6A7
SLC16A4
SLC22A1
SLC29A4
SLC15A1
SLC5A5
SLC32A1
SLC6A9
Slc5a1
ABCA1
Inhibitor/substrate:
-
Inhibitor
Substrate
In Vivo/In Vitro:
-
In Vitro
In Vivo
Species:
-
Animal (unspecified)
Baboon
Cow
Dog
Fish
Frog
Guinea pig
Hamster
Human
Killifish
Mammal (unspecified)
Monkey
Mouse
Mussel
Pig
Plasmodium falciparum
Rabbit
Rat
Rodent (unspecified)
Sheep
Streptomyces peucetius
Research Methods:
-
Animal
Cell line
In Vivo
Lactococcus lactis
ND
Oocyte
Primary cells
Proteoliposome
Recombinant
Tissue
Vesicle
Yeast
Transport Parameters:
-
% Inhibition
% maximum response
% transported
1/RI50
Alpha max
Amount
AUC
Biliary
Bioavailability
Brain/plasma ratio
C/M
Cavg
Cellular accumulation
CL
Cmax
Cmin
Concentration
Dose-dependent effect
Drug Transport
EC200
EC50
ED50
Efflux ratio
Emax
f2
FC
Fetal/maternal
Fg
Fh
FICI
Flow
Fluorescence intensity
flux rate(J)
ft
GI50
GI50
Hill coefficient
I0.5
IC20
IC25
IC50
IC90
Imax
Inhibition Activity
inhibitor or not
ka
Kact
Kd
Kel
Ki
Km
Kp
milk/plasma
mRNA
MRT
net flux ratio
Not Determined
Papp
Pc
Pdif
Peff
Permeability
PK (unspecified)
Protein expression
PSeff
PSinf
Resistance
Substrate Activity
Substrate or not
T1/2
Tmax
Transport Change
Transport Rate
Transport ratio
unspecified
Drug uptake
Urine excretion
Vd
Vmax
Vz
Submit
Tip
Before submitting
, users should prepare a valid SMILES in case of errors.
SMILES or Name
SMILES or Drug Name
Example
Submit
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