|
|
| ID |
IST028 |
| Transporter Name |
ABCA1 |
| Full Name |
ATP-binding cassette, sub-family A , member 1 |
| Species |
Human |
| Aliases |
TGD
Tangier disease
|
| Gene Name |
ABCA1
|
| Gene Full Name |
ATP-binding cassette, sub-family A , member 1
|
| Gene ID |
19
|
| Structure |
https://www.uniprot.org/uniprotkb/O95477/entry#structure
|
| Location |
Widely expressed, but most abundant inmacrophages. |
| Significant Polymorphisms |
rs12003906, rs2230806,rs2230808
|
| Regulatory Requirements |
NO
|
| Desease |
None
|
| Function |
Involved in the efflux of intracellular cholesterol and phospholipids and their transfer to apoliproteins to form nascent high density lipoproteins/HDLs.
|
| Source |
PDB, VARIDT
|